Maria Holic - Wallpaper and Scan Gallery

Maria+Holic tells the story of a high school girl, Kanako Miyamae, whose extreme phobia of men makes her break out in hives whenever she is touched by one.
In her quest for love, she transfers to the all-girls school her mother used to attend. She immediately happens on an ideal mate Mariya Shido, who, unfortunately for her, is a rather sadistic boy in drag.

When I read the summary, I thought it sounded really strange and not at all the kind of thing I'd like. But then I watched the first episode for kicks and was surprised at how much I enjoyed it. Mariya's personality is probably the main clincher. (More specifically, Yuu Kobayashi is awesome and does the octave voice switches amazingly well!)